Why do ichthyosis patients have so many scales on their bodies? Today, Zhangjian Ichthyosis Care Center will explain to you.

 Skin metabolism refers to the growth cycle of skin epidermal cells from the basal layer (newborn cells) to the "dead" stratum corneum. The skin metabolic cycle of normal people is 28 days, while that of ichthyosis patients is only 3-5 days. For ichthyosis patients , the growth of epidermal cells from the basal layer to the stratum corneum is hindered due to genetic problems, and some newborn cells of basal layer prematurely senesce and become dead cells due to loss of nucleus or cell function atrophy.

For example, just like the life cycle of human beings, normal people from childhood to adolescence to adulthood to old age and die. The skin of ichthyosis patients stops growing from the childhood stage, and directly enters the death period after crossing the intermediate stage. At this time, other new cells are still growing continuously, and the countless "dead cells" of the patients continue to accumulate on the surface of the skin, forming scales visible to the eyes, which is why our ichthyosis skin have many scales.